RESIDENTS and visitors to the region are being warned to protect themselves against mosquito-borne diseases such as Ross River virus and Barmah Forest virus.

Deputy Chief Health Officer (communicable disease) Dr Annaliese van Diemen said Ross River virus had been detected in mosquitoes in urban Mildura.

She said these viruses could cause symptoms including joint pain and stiffness, headache, fever, rash and fatigue.

"The best protection from these diseases is to avoid mosquito bites — protective measures include regularly using mosquito repellent containing picaridin or DEET on all exposed skin, wearing long, loose fitting clothing when outside, and ensuring accommodation, including tents, are properly fitted with mosquito nettings or screens," Dr van Diemen said.

"Doctors should consider the possibility of mosquito-borne disease in patients presenting with a compatible illness, especially after travel to rural or regional Victoria."

A blood test early in the illness can indicate potential acute infection and should be repeated two weeks later for confirmation.

"As COVID-19 restrictions ease, there are greater opportunities to travel around Victoria and enjoy increased outdoor activity. Taking measures to avoid mosquito bites is therefore a critical step to protect against diseases," Dr van Diemen said.